Damion Cook will make his first NFL start since 2004 today against the Texans. Cook replaces Edwin Mulitalo, who's inactive. Offensive coordinator Jim Colletto described Mulitalo as "fatigued" earlier this week.

Defensive tackle Chuck Darby (calf) and cornerback Travis Fisher (knee) also are inactive for the Lions, as is newly signed receiver John Standeford. Shaun Cody will start in place of Darby, Brian Kelly in place of Fisher, and rookie defensive tackle Andre Fluellen is active for the first time this year.